The Actions of Antibiotics: Tetracyclines, Aminoglycosides, and Lincosamides
Antibiotics are a type of drug used to treat bacterial infections. Three of the most common types of antibiotics are tetracyclines, aminoglycosides, and lincosamides. Tetracyclines are broad-spectrum antibiotics that are effective against both gram-positive and gram-negative bacteria. They work by inhibiting bacterial protein synthesis, which prevents bacteria from growing and reproducing. Aminoglycosides are also broad-spectrum antibiotics, but they work by interfering with the bacterial cell wall and inhibiting the production of essential enzymes The Actions of Antibiotics: Tetracyclines, Aminoglycosides, and Lincosamides. Finally, lincosamides are narrow-spectrum antibiotics that are effective against gram-positive bacteria. They work by interfering with the bacterial cell membrane, preventing the bacteria from taking up essential nutrients. In addition to the direct action on bacterial cells, antibiotics also have an indirect action. They can stimulate the immune system to fight off the infection, or they can act synergistically with other antibiotics to enhance the effectiveness of their action. For example, aminoglycosides have been shown to have an additive or synergistic effect when combined with tetracyclines (Garcia et al., 2006). Cont…
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